规格：50µL/100µL
货号：PN0187
价格：1350元/50µL；2200元/100 µL
全称 | Tyrosine 3-monooxygenase |
别名 | TH, Th, DYT14, DYT5b, TYH, tyrosine hydroxylase, Tyrosine hydroxy |
抗体来源/类型 | Rabbit Polyclonal |
交叉反应 | Human, Mouse, Rat, Monkey |
产品应用 | WB：1：500-1000 IHC：1：500-2000 IF： 1：500-2000 |
理论分子量 | 62kDa |
细胞定位 | 细胞质，轴突 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | Recombinant protein corresponding to Mouse Tyrosine Hydroxylase
|
亚 型 | IgG |
纯化方法 | Affinity purification |
Uniprot ID | P24529 |
缓 冲 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存条件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecµLar oxygen(O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine(adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines.
